Advertisement

Adverse reaction to metal debris in a consecutive series of DUROM™ hip resurfacing: pseudotumour incidence and metal ion concentration

Abstract

Introduction

The aim of this study was to evaluate the incidence of adverse reactions to metal debris (ARMD) in a consecutive series of DUROM™ Hip Resurfacing Arthroplasty (HRA) at mid-term follow-up.

Methods

Between October 2003 and March 2007 a total of 134 consecutive DUROM™ HRA in 121 patients were performed at our institution. Follow-up could be obtained in 101 unrevised patients (83%) at a mean time of 8.51 ± 0.97 years postoperatively and included patient-related outcome measurement, plain radiographs, MARS-MRI as well as whole blood metal ion assessment.

Results

17 (16.5%) out of 103 hips revealed pseudotumour occurrence in MRI investigation, 1 (10.6%) with a diameter of ≥2 cm. Higher incidence of pseudotumours was found patients with femoral component size <50 mm. 38 patients had elevated cobalt levels, 36 of them (35%) in the range of 2-7 μg/l and 2 patients (1.9%) at a rate of >7 μg/l. In contrast to cobalt determination, only elevated chromium values showed a positive association with pseudotumour occurrence and size.

Discussion

A significant proportion of patients developed pseudotumours and metal ion elevation in a consecutive cohort of DUROM™ HRA after mid-term follow-up. The incidence, however, seems not to differ from results of other well performing resurfacing brands; clinical relevance of our findings is unclear. Regarding potential local as well as systemic effects of metal particle release, close follow-up of patients is essential, even with clinically well-performing implants.

Hip Int 2017; 27(4): 343 - 348

Article Type: ORIGINAL RESEARCH ARTICLE

DOI:10.5301/hipint.5000468

Authors

Albrecht Hartmann, Jan-Dirk Kieback, Jörg Lützner, Klaus-Peter Günther, Jens Goronzy

Article History

Disclosures

Financial support: This project was funded by Zimmer Inc.
Conflict of interest: AH: paid lectures for Infectopharm, Aesculap, Link, Zimmer. JL: research support from Aesculap, Mathys, Smith & Nephew, Stryker, Zimmer; paid lectures for Aesculap, Bayer, Linvatec, Link, Mathys. KPG: research support and personal fees from Aesculap, Link, Zimmer. JDK: None. JG: None.

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.

Authors

Affiliations

  • University Centre of Orthopaedics and Traumatology, University Medicine Carl Gustav Carus, Technical University Dresden, Dresden - Germany
  • Department of Orthopaedics and Trauma Surgery, University of Bonn, Bonn - Germany

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.